With a lifelong commitment to antiretroviral therapy (ART), people living with HIV face new challenges to their health-related quality of life (HRQoL) that demands management guided by patient perspectives. Patient-reported outcome measures (PROMs) are important tools that provide insight into the PLWH’s experience with HIV, revealing non-specific symptoms, behaviours and psychological elements that cannot be measured. The goal of this education is to ensure that HIV specialists are cognisant of the need to optimize health-related quality of life (HRQoL) in PLWH, and have the confidence and competence to utilise PRO tools in routine clinical care to identify individualised needs and priorities that are not easily observed that may influence treatment choice.