Organized by GATE and the Trans Men & HIV Working Group, this groundbreaking symposium is dedicated to integrating trans men and gender diverse persons assigned female at birth (AFAB) into the HIV response. With the Global AIDS Targets 2025 fast approaching, HIV continues to disproportionately impact the TGD community. The exclusion of trans men and AFAB persons from the response remains a significant barrier to achieving equity in healthcare. The symposium aims to change the narrative and highlight innovative approaches to inclusion by bringing together diverse experts, including researchers, policymakers, health professionals and activists. Participants will engage in dynamic discussions and explore emerging evidence that the inclusion of marginalized groups can significantly enhance health responses. Attendees will gain a deeper understanding and practical strategies to prioritize inclusivity and ensure access to care for all, regardless of gender identity.